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Highlights
• Since the last situation report published on 2 March 2023, 323 new mpox cases (0.4% increase in total cases) and 11 new related deaths have been reported to WHO.
• Globally, the number of mpox cases continues to slowly decline, with the Americas remaining the region with most of the reported cases, while transmission and reporting are more continuous and sustained in the African region with no clear downward trend. In the other regions, sporadic cases and small clusters are being reported.
• This situation report provides an update on the clinical presentation and management of severe mpox and on mpox deaths. In the current outbreak, all reported deaths have occurred in adult males, most of whom were immunocompromised, either due to untreated or uncontrolled HIV Infection or other immunocompromising conditions.