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Emily Fuggetta's first time on horseback since losing her leg and her horse in a tragic accident six months before.

After devastating accident, woman gets back in the saddle

Comedian Zach Anner has cerebral palsy but keeps fans laughing on his YouTube channel.

Comedian with cerebral palsy talks humor, Oprah and giving back

Plus-size runner leads the way for overweight athletes

Dr. Joel Salinas, a neurologist at Massachusetts General Hospital, has a rare trait that allows him to feel his patients' pain.

This doctor can feel your pain

How art helped save addict after accident

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Teenager with rare genetic disorder shoots and scores

Phil Southerland was told he would die young from diabetes. But he beat the odds by becoming a competitive cyclist and helping other diabetics along the way.

Cyclist turns a death sentence into a race against diabetes

Brittany Tagliareni plays in a singles match at the INAS World Tennis Championships in Bolton, England, in 2017.

Tennis player with autism slices up the competition

Lani Dickinson is a professional dancer, who was born without an left arm.

Dancer with one arm shows beauty has no bounds

Cindy Martinez met her husband David while they were serving in the Marine Corps.

Marine veteran battles flesh-eating bacteria: 'It was life over limb'

Fearless boxer finds new life after health scare

Todd Vance is using mixed martial arts to help veterans with PTSD come to grips with civilian life.

Army veteran starts 'fight club' to help others with PTSD

Ryan Speedo Green performed as Mandarin in Puccini's "Turandot" at The Metropolitan Opera during the 2012-13 season.

Opera singer: Music saved my life

Alex Jinkinson is launching her career as a pop singer under the name Ali J.

Aspiring pop singer finds her true self after intersex diagnosis

Zimmern learned to cook from his grandmother as a child in New York City.

A one-way plane ticket saved Andrew Zimmern's life

Yousef Erakat went from battling bipolar depression to having more than 12 million fans on YouTube.

YouTube star on bipolar depression: 'I am proof that nothing can stop you'

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How radical tattoos helped her fight breast cancer

Danelle Umstead competed in the women's visually impaired slalom event at the 2010 Winter Paralympics in Vancouver.

Hurtling through the dark: Blind skier races up to 70 mph

Jake Olson doesn't look at football like his teammates. The long snapper for the University of Southern California is blind.

Blind football player defies odds on the field and in life

LONDON, ENGLAND - JULY 31: Allison Schmitt of the United States celebrates after winning gold in the Women's 200m Freestyle final on Day 4 of the London 2012 Olympic Games at the Aquatics Centre on July 31, 2012 in London, England. (Photo by Ezra Shaw/Getty Images)

Olympic medalist swimmer takes on depression with help of Phelps, others

Shannon Kopp battled bulimia for years until she found comfort from shelter dogs who saved her life.

Among shelter dogs, finding the strength to fight bulimia

Painting allows blind artist to see a world of color

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Together in sickness, married in health

Fulfilling goals of a lifetime, with help from bariatric surgery

Despite losing her leg, Kate Foster is back in gymnastics and competing with her teammates.

Gymnast: 'It was my leg or my life'

Despite battling cerebral palsy, Jason Benetti landed his dream job with the Chicago White Sox in January.

White Sox announcer with cerebral palsy finds his calling

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Triple amputee doctor: Disability doesn't define you

Devastating accident inspires man to run half-marathon

Despite battling cerebral palsy, Jason Benetti landed his dream job with the Chicago White Sox in January.

'Dancing with the Stars' winner wants to empower others who are deaf

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Paralyzed woman hikes the Appalachian Trail

Westerman and dance partner David Mineo.

Dancer: 'I am so much more than my wheelchair'

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'Shark' takes a bite out of dyslexia

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100-pound weight loss helps 'broken' man rebuild

Erik Weihenmayer is the first blind person to reach the summit of Mount Everest.

'All of us in a way are climbing blind'

Emily Fuggetta's first time on horseback since losing her leg and her horse in a tragic accident six months before.

After devastating accident, woman gets back in the saddle

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Doctor with spina bifida defies expectations

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Portrait of a 6-year-old artist with autism and her therapy cat

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Violinist cheats death, fulfills destiny

Beating heroin is more than 12 steps; it's 18 years and going

She raised millions for the cystic fibrosis breakthrough she needs

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Champion pool player turns pain into will to win

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The sky's the limit for blind pole vaulter

Dever playing lacrosse after part of his left leg was amputated.

Cancer took athlete's leg but he stayed in the game

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Parkinson's patient fights disease with magic and music

His battle with ALS empowered her to live

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Actress fights bipolar disorder stigma with comedy

My sister, the addict -- and her recovery

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Living an adult life in a boy's body

Teen with Tourette's vlogs to erase stigma

Jake Olson doesn't look at football like his teammates. The long snapper for the University of Southern California is blind.

Blind football player defies odds on the field and in life

Emmanuel stars as 'Super Love Boy' in his comic book "Bully Me? No Way! I Got the Power."

A boy's birthday wish: honoring his mom's memory

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After experimental treatment, 24-year-old is learning how to live

She lost 185 pounds to pursue the 'heart of a warrior'

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'I no longer see a fat little boy,' says a man overcoming body dysmorphia

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Mom with ALS: My disease will make my daughter stronger

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New steps for blind, paralyzed adventurer

Mackenzie Walker lost 100 pounds before she turned 15 years old.

15-year-old loses 100 pounds to reach bodybuilding dream

How yoga changed her life

Teen overcomes anorexia through yoga

Janine Shepherd earned her pilot's license within a year of her first flight

Olympic hopeful re-imagines her life

Adam Park weight loss journey

How one teen began his 165-pound weight loss journey

Getting a job saved this 19-year-old's life

Collins is pictured with her daughter, Jada, who now plays volleyball. She is teaching her how to have a healthy relationship with her body.

Beyond the mirror: How one woman learned to love herself

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In sickness and in help

Father loses son to addiction, ends up in recovery himself

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Embracing life with a bucket list

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A mother's grief: Why I cried the day my son turned 6

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Blind swimmer holds 12 national records

Reddit's 'bullies' pushed me to fight weight gain

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When your daughter has anorexia

100 days without fear

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Dishwasher lost 100 pounds by eating on the job

Jiujitsu Bronze medalist Michelle Anthony (right) with her boyfriend.

After divorce, she fought off fear with jiujitsu

From heroin-fueled bank robber to family man

Defeating the cycle of self-sabotage

Kelly Hager survived a coma and came back to running a successful business, with the help of her team.

How a coma made me a happier person